Vaping has not been around for long enough to know the risks of long-term use. While vaping is less harmful than smoking, it is unlikely to be totally harmless.
Children and non-smokers should never vape.
The healthiest option is to not smoke or vape. So, if you are vaping to stop smoking, you should aim to eventually stop vaping too.
Once you have been vaping for a while and feel sure you will not go back to smoking, you can aim to stop vaping too by gradually reducing your frequency of vaping and the strength of nicotine in your e-liquid over time. Many vapers find they get to this stage after about 12 months.